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{НзОгСИ—О О
X
(НзОгСН-с/ NCI
[Н3О2СН —0Х ^0 |
(НзС)гСН-о' V j Isofluorophate \
USP 2409039 (Monsanto; ert. 1946; Anm. 1944). J: D. F. P. Inj. (Sumitomo)
USA: Floropryl® (Merck Sharp + Dohme)
Isoflupredon
338-95-4
338-98-7 Acetat
Glucocorticoid
9-fluoro-11/3,17,21-trihydroxypregna-l,4-diene-3,20-dione
НзС-СО-О-СНг
V=0
Fludrocortisonacetat (s. S. 407)
Se02
Selendioxid
1НэС)зС —OH /Ra-Ni ferf-Butanol / Raney-Nickel
i H3C-CO-O-CH2
Isoflupredonacetat
DBP 1096900 (American Cyanamid; Anm. 1959; USA-Prior, 1958). Mikrobiologische Dehydrierung mit Corynebacterium simplex (A.T.C.C. 6946); USP 2837464 (Schering Corp.; ert. 1958; Prior. 1955).
Weiteres Verfahren:
DBP 1159947 (Merck & Co.; Anm. 1956; USA-Prior. 1955).
GB-P 826364 (Merck & Co.; Laufzeit ab 1956; USA-Prior. 1955).
USA: Predef® 2x (Upjohn)
Biorinil® (Farmila)-Komb. Menaderm® simp. (Menarini)
Isomethepten
503-01-5
6168-86-1 Hydrochlorid 5984-50-9 Tartrat
sympathisches
Spasmolyticum
A/,l,5-trimethyl-4-hexenylamine
C=CH~CH2-CH2-C + ch3nh2 НзС7 VCH3
H2 /Raney-Ni
2-Methyl-5-oxo-2-hepten
Methylamin
c=ch-ch2-ch2-ch-nh-ch3
нэс СНз
Isomethepten
USP 1972450 (Knoll; ert. 1934; D-Prior. 1931).
USP 2230753 (E. Bilhuber; ert. 1941; D-Prior. 1937). USP 2230754 (E. Bilhuber; ert. 1941; D-Prior. 1937).
I: Octinum® (Knoll)
J: Cesal® (Dainippon)-Komb.
USA: Midrin® (Camrick) Octin® (Knoll) Octinum® (Knoll)
Isoniazid - Isoprenalin I 503
Isoniazid
54-85-3
Tuberkulostaticum
isonicotinic acid hydrazide
v>
с + h2n-hh2 oc2hs
Isonicotinsaure-
ethylester
/
Hydrazin
NH~NH2 . Isoniazid I
H. Meyer, J. Maliy, Monatsh. Chem. 33, 393 (1912). USP 2 596069 (Roche; ert. 1952; Anm. 1952). USP 2 830994 (Distillers; ert. 15.4.1958; GB-Prior. 29.6.1955). DBP 1116667 (BASF; Anm. 3.7.1956). Komb. mit Protionamid und Dapson: DAS2340515 (Saarstickstoff-Fatol; Anm. 10.8.1973).
D:
F:
GB:
I:
Cedin® (Lyssia)
etibi-inh® (Saarstickstoff-Fatol)-Komb. INH-Burgthal® (Conzen)
Isoni. ProDap (Saarstickstoff-Fatol)-Komb. Isoprodian® (Saarstickstoff-Fatol)-Komb. Isozid (Saarstickstoff-Fatol)
Neoteben® (Bayer)
Rimifon® (Roche)
Tb-Phlogin® (Heyi)
Tebesium® (Hefa-Frenon)
INH-B 6 Corbiere (Millot)-Komb. Isoniazide Lavoisier (Chaix et du Marais) Rimifon® (Roche)
Rimifon® (Roche)
Cin-Vis® (Vis)
Idrazil® (Bracco)
Nicazide® (Wassermann)
Nicazide® (Farmitalia)
Nicozid® (Piam)
USA:
Tibirzina® (Farmachimica Ital.) und Komb.-Praparate Anteben® (Dainippon)
Diazid® (Nippon Shinyaku)
Hycozid® (Takeda)
Hydra® (Otsuka)
Iscotin® (Daiichi)
Niazid® (Sankyo)
Niplen® (Tanabe)
Sumifon® (Sumitomo)
Tuberon® (Shionogi)
Dow-Isoniazid™ (Dow)
Isoniazid Tabl. (Lilly)
Hyzyd® (Mallinckrodt)
Niconyl® (Parke-Davis)
Nydrazid® (Squibb)
Niadox® (Bames-Hind)-Komb.
Pasna® Tri-Pack Granules (Bames-Hind)-Komb.
Isoprenalin
(Isoproterenol)
7683-59-2 59-60-9 Bitartrat 51-30-9 Hydrochlorid 299-95-6 Sulfat
Broncholyticum;
(Dermaticum)
u-( isopropylaminomethyl)protocatechuyl alcohol
CH3
но-<^ ^-c-ch2-ci + h2n-ch-ch,
но-i Vc-ch,—NH-CH-CH3
a/-Chlor-3,4-dihydroxy-
acetophenon
Isopropylamin
H2 / Pd-C
CH3 ]
; ночГ>сн-сн2-,н-сн-снз| I OH I
Isoprenaiin
504 I Isoprenalin - Isopropamid-jodid
USP 2308232 (BoehringerIng.; ert. 1943; D-Prior. 1939). DRP723278 (Boehringer Ing.; Anm. 1939), Razematspaltung mit (-f-)-Weinsaure: USP 2 715141 (Delmar Chemicals; ert. 1955;Anm. 1952).
GB:
Aludrin® (Boehringer Ing.) AIudrin^-Dosier-Aerosol (Boehringer Ing.) Bellasthman Medihaler® (Kettelhack Riker) Ingelan®-Gel/Salbe (Boehringer Ing.) Aleudrine® (Badrial)
Dilobron® (Labaz)-Komb.
Isoprenaline Berthier (Berthier-Derol) Isuprel® (Winthrop)
Aleudrin® (Lewis)
Iso-Autohaler® (Riker)
Lomupren® (Fisons)
Medihaler-Iso® (Riker)
Meterdos-Iso® (Sinclair)
Prenomiser® (Fisons)
Saventrine® (Pharmax)
J:
USA
Asthpul® Sol. (Nippon Shoji) Isomenyl® (Kaken) MedihaJcr-Iso® (Dainippon) Protemol® (Nikken)
Sedansol „Iso“ (Nippon Zoki) Sooner® (Kaken) Duo-Medihaler® (Riker) Isuprel® (Winthrop)
Luf-Iso® (Mallinckrodt) Medihaler-Iso® (Riker) Nebair™ (Warner-Chilcott) Norisodrine® (Abbott) Vapo-N-Iso® (Fisons)
Isopropamid-jodid 71-8I-8 Anticholinergicum;
Spasmolyticum
(3-carbamoyI-3,3-diphenylpropyl)diisopropylmethylammonium iodide
Diphenyl-
acetonitril
1. NaNHj CH{CH3)2
2. Cl-CH2-CH2-N
4CH(CH3)5
1 Natriumamid
2 2-Oiisopropylamino-ethylchlotid
c- ^CHICH^
''ch2-ch2-n
CH(CH3)2
H2S04
’C' CHiCH3)2
\h2-ch2-n
4CH(CH3)j
Methyl-
jodid
Q
,С0-МН2
CH3
OCH2-CH2-N-CH(CH3)2
1
CH(CHt)2
Isopropamid-jodid
GB-P 772921 (Janssen; Anm. 1955; NL-Prior. 1954). DBP 1003744 (Janssen; Anm. 1955; NL-Prior. 1954). P. Janssen et al., Arch. Int. Pharmacodyn. Ther. CUT, 82 (1955). USP 2 823233 (Bristol; ert. 1958; Anm. 1954).
D: Priamide-Eupharma® (Janssen) I: Dipramid Valeas (Valeas)
F: Priamide® (Delalande) u. Komb.-Praparate
GB: Tyrimide® (Smith Kline & French) J: Marygin® M (Sumitomo)
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