Атлас заболеваний полости рта - Ланге Р.П.
ISBN 978-5-9704-0578-9
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4-amino-5-chloro-/V-[2-(diethylainino)ethyl]-o-anisamide
Antiemeticum;
Magentherapeuticum
OH
H2N-<^^-COOH
4-Aminosalicyl3aure
OH
снэ6н/[н*] л (h3c-co)2o -■-1—H2N—(( у-СООСНз —--
4-Ammosalicylsaure-
methylester
OH
H3C - CO- NH-<^_^-COOCH3
Dimethyl-
sulfat
РћРЎРќР·
H3C-CO-NHHf^COOCH3 H3C-CO-NH-0.
РћРЎРќР—
РЎРћРћРЎРќР·
&-Acetamido-2-methoxybenzoe-
sauremethylester
4-Acetamido-5-chlor-2-methoxy-
benzoesauremethytester
1. H2N-CH2-CH2-N(C2H5)2 / Al[OCH(CH3)2 ],
2. HCl_
1 jV.iV-OiethylethylendiamiCi /Alumimumiso-
propylat
h2n
РћРЎРќР·
C2H5
-CO-NH-CH2-CH2-N
C2H5
Metoclopramid
DOT 1,66(1965).
DBP 1233 877 (Soc. d’Etudes Scientifiques et Industrielles de l’lle-de-France; Anm. 14.7.1962; F-Prior.
25.7.1961).
FP 1 313 758 (Soc. d’Etudes Scientifiques et Industrielles de l’lle-de-France; Anm. 25.7.1961).
USP 3 177 252 (Soc. d’Etudes Scientifiques et Industrielles de l’lle-de-France; ert. 6.4.1965; F-Prior.
25.7.1961).
USP 3 219 528 (Soc. d’Etudes Scientifiques et Industrielles de l’lle-de-France; ert. 23.11.1965; F-Prior.
25.7.1961, 5.8.1961,4.11.1961).
USP 3 357 978 (Soc. d’Etudes Scientifiques et Industrielles de l’lle-de-France; ert. 12.12.1967; F-Prior. 5.3.1963).
594 M Metoclopramid - Metolazon
Weitere Verfahren:
DOS 1 932 512 (Huhtamaki; Anm. 26.6.1969; SF-Prior. 28.6.1968).
DAS 1960130 (Yamanouchi; Anm. 29.11.1969; J-Prior. 2.12.1968, 9.12.1968, 4.4.1969).
DAS 1 966453 (Yamanouchi; Anm. 29.11.1969; J-Prior. 9.12.1968).
DAS 2 102 848 (Delmar; Anm. 21.1.1971; USA-Prior. 21.1.1970).
DAS 2 119724 (Teikoku Hormone Mfg.; Anm. 22.4.1971; J-Prior. 24.4.1970).
DAS 2 162 917 (Soc. d’Htudes Scientifiques et Industrielles de ITle-de-France; Anm. 17.12.1971;
J-Prior. 21.12.1970).
DAS 2 166 117 (Teikoku Hormone Mfg.; Anm. 22.4.1971; J-Prior. 24.4.1970).
DAS 2166 118 (Teikoku Hormone Mfg.; Anm. 22.4.1971; J-Prior. 24.4.1970).
DAS 2 342 934 (Delmar; Anm. 24.8.1973; GB-Prior. 25.8.1972,13.12.1972,16.4.1973).
DAS 2365 988 (Heumann + Co.; Anm. 12.7.1973).
Ausgangsverbindung:
DAS 2335 439 (Heumann + Co.; Anm. 12.7.1973).
D: Metoclopramid (Dolorgiet; Lvssia)
PaspertaseВ® (Kali-Chemie)-Komb.
PaspertinВ® (Kali-Chemiej F: PrimeranВ® (Delagrange)
GB: MaxolonВ® (Beecham)
PrimperanВ® (Berk)
I: AnandaВ® (Bonomelli-Hommel)-HCl, Monohy-drat
Clodil-TonВ®(Ion)-HQ, Monohydrat ClopanВ® (Firma)-HCl DigitresВ® (Scalari)-HCI KilozimВ® (Agips)
MetocobiiВ® (Beta)-HCl NadirВ® (Oti)-HCl
USA:
PlacitrilВ® (Sigurta)
PlasilВ® (Lepetit)-HCl, Monohydrat QuantoВ® (Mediolanum)-Komb. RegastrolВ® (Sarm)-HCl ViscalВ® (Zoja)-Dichlorid, Monohydrat ZimozimВ® (Medal)-Komb. DonoponВ®-GP (Sana)
PeraprinВ® (Taiyo Yakuko Takayama) PrimperanВ® (Fujisawa)
PutoprinВ® (Mohan)
TerperanВ® (Teikoku Zoki)
RegianВ® (Robins)
Metolazon
17560-51-9
Diureticum; Antihype rtomcum
7-chloro-l,2,3,4-telrahydro-2-methy]-4-oxo-3-o-tolyl-6-quinaxolinesulfonamide cu ^ CI^^^NH-roOCzHs
XX
5-Chlor-2-
methylamlin
+ Cl—COOC2Hs
Chlorameisen-
saureethylester
1. ClSOjH
2. NH3_
I. Chlorsulfon-
saure
5 -Chlor - A/-ethoxycarbonyl -2-methylanilin
xxi:
NH-C00C2Hs
H2N-SO2'
4-Aminosulfonyl-W-ethoxycarbo-
nyl-2-methylamlin
C,rr^В°
h2n-so/^YВ°
HzN
HjC’
-p
2-MВ»thylar\ilin [o-Toluidir)
Cl^^NH-COOC2H5
H2N - S02'^^'C00H
5-AmmosulfDnyl-4-chlor-A/-ethoxy-carbonyi - anthranilsaure
nh2
H2N-S02
6-Armnosulfonyl-7-chlor-
isatinsaureanhydrid
2-Amino-5-ammosiilfonyi-4-cMor-
o-tolylbВ«nzamki
Metolazon - Metopimazin - Metoprolol M 595
Acelaldetiyd-
dimethylacetal
H3C —CHiOCH; j; ! [ HjSOj ]
H2N-S02
Cl
Metolazon
DOT 9,498 (1973).
DAS 1 620740 (Pennwalt; Anm. 24.12.1966; USA-Prior. 3.1.1966).
DOS 2 131 622 (Pennwalt; Anm. 25.6.1971; USA-Prior. 29.6.1970).
USP 3 360518 (Wallace + Tiernan;ert. 26.12.1967; Prior. 3.1.1966).
USP 3 557111 (Wallace -f Tieman;ert. 19.1.1971; Prior. 29.3.1968).
USP 3 761480 (Pennwalt; ert. 25.9.1973; Prior. 10.7.1968, 7.11.1969, 15.3.1972).
DOS 2035 657 (Sumitomo; Anm. 17.7.1970; J-Prior. 22.7.1969, 25.2.1970, 27.3.1970).
D: ZaroxolynВ® (Searle) USA: DiuloВ® (Searle)
GB: ZaroxolynВ® (Farillon) ZaroxolynВ® (Pennwalt; Searle)
MetenixВ® (Hoechst)
Metopimazin 14008-44-7 Antiemeticum
l-[3-[2-(methylsulfonyl)phenothiazin-l0-yl]propyl]-isonipecotamide
2-Methylsulfony(-
phenothiazin
Piperidin-4-caroon-saureamid
{Isompecotirsaureamid)
IO-(3-Chlorpropyl)-
2-methylsulfonyl-
phenothiazin
DOT 1, 66(1965).
DBP 1 092 476 (Rhone-Poulenc; Anm. 14.4.1959; F-Prior. 24.4.1958).
F: VogaieneВ® (Theraplix)
I: Vogaiene (Roger Bellon)
Metoprolol
37350-58-6 56392-17-7 Tartrat
Betablocker
(В±)- l-(isopropylamino)-3-[p-(2-methoxyethyl)phenoxy]-2-propanol
596 M Metoprolol - Metrizamid
H3CO-CH2-CH2 —
4 -(2-Methoxyethyl)-phenol
CI-CH2
Epichlorhydrin
— CH2 — CH2 —у*~0 — CH2—<J
РќР·РЎРћ
1,2-Epoxy-3- [4-(2-methoxyethyl)-phenoxy]-propan
HjN-CWCHah
CH3
НзСО ” CH2 - CH2-<^^“0-снг ~ CH - CH2 - NH - CH-CH3
РѕРЅ
Metoprotol
