- ..
( ):
Metabioticon B.G.® (Boniscontro & G.) J: Adramycin® (Sanko)
Metac® (Dima) Rondomycin® (Taito Pfizer)
Metacil® (Ibirn) Metaclin® (Medicil) USA: Rondomycin® (Wallace)
Metahexamid 565-33-3 Antidiabeticum
l-(3-amino-p-tolylsulfonyl)-3-cyclohexylurea
H3C-<f~VSOZ-NH2 OCOOCiHs/KiCOi/AcrtH^ НзС—^—S02—NH—COOC2H5
\_/ L Chlorameiseri- \—/
/ saureethytester ^ /
НзС-СО-NH H3C-CO-NH
3-Acetamino-4-methylbenzol-
sulfonamid
S02 —NH-C-NH—(^> SOz-NH-C-NH-<^)
Cyclohwyt- НзС
jmm
H3C-CO-NH H2N
Metahexamid - Metampicillin - Metapramin M 569
GB-P 831043 (Boehringer, Mannh.; Anm. 1958; D-Prior. 1957).
F: Isodiane® (Servier)
Metampicillin 6489-97-0 6489-61 -8 Na-Salz Antibioticum
[a-(methyleneamino)benzyl]penicillin 0r3,3-dimethyl-6-[2-(methyleneamino)-2-phenylacetamido]-7-oxo-4-thia-l-azabicyclo[3.2.0]heptane-2-carboxylic acid
„ ° ^ ? V V-CH-C — NHH—kS4/CH3 NaHCOa /СН3О NH, CH3 COOH ,—. Я H H 1Г\— CH - С - NH -i—KSW-CH3 К о^^снэ СНг COOH
AmpiciUin Metampicillin
(s. S. 50)
GB-P 1081093 (Soc. d’Etudes de Recherche et d’Appiicat. Scientifiques et Medicals; Anm. 17.3.1964; Laufzeit ab 12.3.1965).
F: Magnipen® (Clin Midy) 1: Magnipen® (Midy)
Metapramin 21730-16-5 Antidepressivum
21737-55-3 Hydrochlorid
10,1 l-dihydro-5-methyl- 10-(methylamino)-5H-dibenz[b,f]azepine
j Metapramin (
DOF 6,479 (1981).
FP-M 6616 (Rhone Poulenc; Anm. 14.4.1967).
SA-P 6 800 345 (Rhone Poulenc; Anm. 19.6.1968; F-Prior. 18.1.1967, 9.11.1967). Weiteres Verfahren:
■DOS 2 159678 (Rh6ne Poulenc; Anm. 1.12.1971; F-Prior. 1.12.1970).
F: Rodostene® (Rhone Poulenc)
570 M Metandienon - Metaraminol
Metandienon
(Methandienone;
Methandrostenolon)
72-63-9
Anabolicum
17/3-hydroxy- 17-methylandrosta-1,4-dien-3-one
-*СНз a) SeGi/teri-Amylalbohcl b| mikroixofcgische
j 4 Eiserpulver/Ethyl- Oder Dehvdneruno
acetat {Oidymeffaf
MethyUestosteron (s. S. 588)
a USP 2 900 398 (Ciba; ert. 1959; CH-Prior. 1956).
Ch. Meystre et al., Helv. Chim. Acta 39, 734 (1956). b F. Vischer et al., Helv. Chim. Acta 38,1502 (1955).
D: Dianaboi® (Ciba)
F: Dianaboi® (Ciba-Geigy)
Dianavit® (Ciba-Geigy)-Komb. GB: Dianaboi® (Ciba)
I: Dianaboi® (Ciba)
Metaboiina® (Guidi)
Metastenol® (Farber-REF) Petbolin® (Ion)
J: Abirol® (Takeda)
Anoredan® (Kodama) USA: Dianaboi® (Ciba)
Metaraminol
54-49-9
33402-03-8 Hydrogentartrat
Sympathomimeticum
(—)-a-(l-aminoethyl)-m-hydrobenzyl alcohol
/r==\ (Giirung]
/)—CH0 + D-Glucose -*
H3C-C0-0
3-Acetoxybenzaldehyd
ch-co-ch3
OH
(-Ы-Hydroxy-И-{3-hydroxyphenyl)-aceton
NH3jH2/Pd-C
s>.
HO
CH-CH-CH3 I I I OH NH,
CO~CH2~CH3 + Cl
,==\ NaOC2H5
HO
3-Hydroxypropiophenon Benzylchiorid
HsCt—ONO
Р-со-снг-сн3
<0>-сиг-о
3 - Benzytoxypropiophenon
Butylritrit
__CH,
CO-C
VN0H
yj~c
H2/Ran«y-Ni
0~?н-?н_снз 0-CH2-C> 0H NH?
Hj/Pd-C |*)-W«if»saure
-► (i)-Metarammol -*• Melaraminol
Metaraminol - Metaxalon - Metenolon M 571
a DRP 555 404 (I. G. Farben; Anm. 1930).
USP 1951302 (Winthrop; ert. 1934; D-Prior. 1930). b DRP 571229 (I. G. Farben; Anm. 1930).
USP 1948 162 (Winthrop; ert. 1934; D-Prior. 1930).
USP 1 995 709 (Sharp & Dohme; ert. 1935; Anm. 1931).
GB-P 396 951 (I. G. Farben; Anm. 1932; D-Prior. 1931).
D: Araminum® (Sharp & Dohme) J: Araminon® (Merck-Banyu)
F: Aramine® (Merck Sharp & Dohme) USA: Aramine® (Merck-Sharp & Dohme)
GB: Aramine® (Merck Sharp & Dohme) Metaraminol Bitartrate (Bristol)
I: Levicor® (Bioindustria)
5-[(3,5-xyIyloxy)methyl]-2-oxazolidinone
h,c H,c
3,5-Dimethyl-
phenoi
Gtycid
3-{3,5 - Dimethyl phenoxy) -propan-1,2-dtoi
Metaxalon
USP 3 062 827 (A. H. Robins; ert. 6.11.1962; Prior. 19.6.1959).
USA: Skelaxin® (Robins)
Metenolon
(Methenolone)
153-00-4
434-05-9 Acetat 303-42-4 Onanthat
Anabolicum
17/3-hydroxy-l-methyl-5a-androst-l-en-3-one
a
H
17/3-Acetoxy-3-oxo-1-androsten
(aus Androstanoton I
O-CO-CH3
\ Ethytengtykcl 2 ChromlVD-oxid
572 М Metenolon - Metformin
О-СО-СНз
1. СНзМдвг 2- Нг01\н* ] _
I Methyl-magnesium-bromid
о-со-сн3
Metenoioracelal
17/3-Hydroxy-3-oxo-1-androsten
CH2N2
Diazo-
methan
(H3C— C0);0 /1 Pyndm 3 Acetanhydnd
Metenolonacetat
a DBP 1152 100 (Schering AG; Anm. 23.11.1960).
DBP 1154 467 (Schering AG; Anm. 22.7.1961). b DBP 1023 764 (Schering AG; Anm. 6.2.1957).
DBP 1072 991 (Schering AG; Anm. 25.10.1958).
DBP 1096 353 (Schering AG; Anm. 11.7.1961).
DBP 1117113 (Schering AG; Anm. 5.12.1959).
DBP 1135 900 (Schering AG; Anm. 27.8.1960).
Ausgangsverbindung:
A. Butenandt, H. Dannenberg, Chem. Ber. 71,1681 (1938).
Weitere Verfahren:
GB-P977 082 (Schering AG; Laufzeit ab 17.3.1961; D-Prior. 6.4.1960, 21.7.1960, 23.12.1960). GB-P 977 083 (Schering AG; Laufzeit ab 17.3.1961; D-Prior. 6.4.1960).
Obersicht:
R. Wiechert, Z. Naturforsch. 196, 944 (1964)
D:
Dacomid® (Schering)-Komb.
Fortabol® (Schering)-Komb. GB:
Neuro-Fortabol® (Schering)-Komb. I:
Primobolan® (Schering) J:
